Prevalence and sociodemographic characteristics associated with benzodiazepines use among community dwelling older adults: The Bambuí Health and Aging Study (BHAS) Prevalência e características sociodemográficas associadas ao uso de benzodiazepínicos por idosos residentes na comunidade: Projeto Bambuí

نویسندگان

  • Araújo Firmo
  • Maria Fernanda Lima - Costa
  • Elizabeth Uchoa
چکیده

Objectives: To assess the prevalence and sociodemographic characteristics associated with benzodiazepine use among communitydwelling older adults. Method: 1606 subjects, aged  60 years, corresponding to 92% of the residents of Bambuí city, participated in this study. The information about medication use was obtained by means of a standard interview and the review of medication packaging. Substances were classified using the Anatomical Therapeutic Chemical Index. Results: The prevalence of benzodiazepine current use was 21.7% (26.7% among females and 14.0% among males). From these, 68.7% had been taking the medication for over one year, 31.3% for over five years and 53.2% were using long half-life benzodiazepines. The medication most frequently used was bromazepam (35.6%), followed by diazepam (22.5%), clonazepam (12.6%) and lorazepam (7.8%). After adjustment for confounders, female gender (RP = 1.93; CI95% = 1.51-2.46) was the only sociodemographic characteristic found to be independently associated with substance consumption. Conclusions: The prevalence of benzodiazepine use in the study population was high, but within the variation observed in developed countries. Chronic use of benzodiazepines and long half-life medications predominated. Descriptors: Elderly; Pharmacoepidemiology; Use of benzodiazepines; Cross-sectional studies; Anxiolitic agents Resumo Objetivos: Determinar a prevalência e características sociodemográficas associadas ao uso de benzodiazepínicos entre idosos residentes na comunidade. Método: Participaram deste estudo transversal 1.606 indivíduos, que correspondem a 92% do total de residentes na cidade de Bambuí-MG com idade  60 anos. As informações sobre uso de medicamentos foram obtidas por meio de entrevista padronizada e verificação da embalagem. A classificação do princípio ativo foi baseada no Anatomical Therapeutic Chemical Index. Resultados: A prevalência do uso de benzodiazepínicos foi de 21,7% (26,7% entre as mulheres e 14,0% entre os homens); 68,7% faziam uso do medicamento há pelo menos um ano, 31,3% há pelo menos cinco anos e 53,2% faziam uso de benzodiazepínicos de meia-vida longa. O medicamento de uso mais comum foi o bromazepam (35,6%), seguido pelo diazepam (22,5%), clonazepam (12,6%) e lorazepam (7,8%). Após ajuste para variáveis de confusão, sexo feminino foi o único fator independentemente associado ao uso de benzodiazepínico (RP = 1,93; IC95% = 1,51-2,46). Conclusões: A prevalência do consumo de benzodiazepínicos na população estudada foi alta, mas dentro da variação observada em países desenvolvidos. O uso crônico e o uso de benzodiazepínicos de meia-vida longa foi predominante. Descritores: Idoso; Farmacoepidemiologia; Uso de benzodiazepínicos; Estudos transversais; Ansiolíticos 1 Public Health and Aging Research Group, Fundação Oswaldo Cruz (FIOCRUZ) and Universidade Federal de Minas Gerais (UFMG), Belo Horizonte (MG), Brazil 2 Post-Graduate Program in Health Sciences, Institute René Rachou, Fundação Oswaldo Cruz (FIOCRUZ), Belo Horizonte (MG), Brazil 3 Departament of Preventive and Social Medicine, Medical School, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte (MG), Brazil 4 Mental Health Departament, Medical School, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte (MG), Brazil Rev Bras Psiquiatr. 2007 Jussara Mendonça Alvarenga,1,2 Antônio Ignácio de Loyola Filho,1,2 Josélia Oliveira Araújo Firmo,1,2 Maria Fernanda Lima-Costa,1,2,3 Elizabeth Uchoa1,2,4

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A population based study on health conditions associated with the use of benzodiazepines among older adults (The Bambuí Health and Aging Study) Estudo de base populacional sobre condições de saúde associadas ao uso de benzodiazepínicos em idosos (Projeto Bambuí)

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تاریخ انتشار 2008